Comparative analysis of allogeneic bone pad and autogenous bone graft in anterior cervical interbody fusion

doi:10.3969/j.issn.2095-4344.2014.39.004

Abstract

Abstract:

BACKGROUND: Surgical treatment is often required for fractures of the cervical vertebrae. Anterior interbody fusion technology is still the main method for the treatment of cervical degeneration or traumatic instability. Here, the self-made oval allogeneic bone pad can adapt to different height and width of the intervertebral space, in line with the physiological shape of the intervertebral space.
OBJECTIVE: By comparison with autogenous iliac crest bone, to evaluate various types of self-designed allogeneic bone pads on anterior cervical interbody fusion.
METHODS: From January 2009 to December 2013, 58 patients with cervical disc herniation were enrolled and subjected to cervical discectomy and anterior cervical interbody fusion. According to different bone grafts, these patients were divided into allogeneic bone pad and autogenous iliac bone groups. The course of disease was 12 to 24 months. The postoperative effect was measured by Japanese Orthopaedic Association (JOA) score, cervical fusion rate, fusion time, operative time, blood loss and rejection rate.
RESULTS AND CONCLUSION: At 6 months postoperatively, the JOA score of two groups had no significant difference at 6 months after treatment (P > 0.05); the cervical fusion rates were 83.7% and 87.8%, respectively, in the allogeneic bone pad and autogenous iliac bone groups, with no significant difference (P > 0.05). Fusion time was higher in the allogeneic bone pad than in the autogenous iliac bone group (P < 0.05). The internal fixators in
the two groups were firmed without loosening, and there was no rejection during the follow-up. Compared with the autogenous iliac crest bone, anterior cervical interbody fusion with allogeneic bone pad can achieve satisfactory effects, which can be better for intervertebral fusion and cannot induce pain due to bone cutting.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: spinal fusion, bone transplantation, internal fixators

CLC Number:

R318

Wang Wei-ji, Guan Yu-cheng, Gao Xi-lin, Ji Ming-hua, Guo Shu-zhang, Fan Xiang-cheng, Ye Si-bo. Comparative analysis of allogeneic bone pad and autogenous bone graft in anterior cervical interbody fusion[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(39): 6252-6257.

Figures/Tables 5

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